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Natural Science - Year II

Unit 59: Krebs and Cellular Respiration

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History Weblecture for Unit 59

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History Lecture for Unit 59: Krebs and Cellular Respiration

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Discovering How Cells Use Energy

Cellular Respiration

The discovery of the process of cell respiration is the result of the work of Sir Hans Adolf Krebs, a biologist born in 1900 in Hildesheim, Germany, who moved to England in 1933 to escape possible persecution by the Nazis. Krebs performed most of his research at Cambridge, Sheffield, and Oxford Universities in England, working out the details of what was then called the urea cycle.

Read about Hans Krebs at the Nobel Prize site.

  • Why did Krebs leave his hospital job at Freiburg-im-Breisgau?
  • Where did he do most of his research?

Fritz Lippmann, another German-born scientist who left Germany to escape the Nazis in the early 1930s, went to work for the Rockefeller Institute (now University). He joined the faculty of Cornell University, and later moved to Harvard. After World War II ended, he continued Krebs's work, and identified the chemical coenzyme A, which provided the link between the two phases of cellular metabolism, glycolysis, and the Krebs' cycle. In 1953, Lippmann shared the Nobel Prize in physiology with Krebs for their work on metabolic processes.

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Further Study/On Your Own